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The abundance of each mass isotopomer was then mathematically corrected to eliminate natural abundance isotopes and normalized to the protein content of each sample

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Propensity score matching (1:1) was used to balance baseline characteristics, and clinical outcomes were compared between the groups

Thus, the lung-gut axis is assumed as a bilateral loop, which would be regulated dynamically by the modulation of the lung or gut immune responses, and is perturbated in acute to post-acute COVID-19 syndrome (Figure 1)